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Indian J Exp Biol ; 1990 Mar; 28(3): 295-6
Article in English | IMSEAR | ID: sea-60419

ABSTRACT

The effect of penicillic acid on isolated frog's heart has been studied along with ions of Na+,K+ and Ca2+. Penicillic acid has been found to inhibit the entry of these ions into cardiac tissue thereby arresting the action of the heart. The blockage can be washed away by perfusion with Ringer's solution.


Subject(s)
Animals , Calcium Channels/drug effects , Caproates/toxicity , Heart/drug effects , Penicillic Acid/toxicity , Potassium Channels/drug effects , Ranidae , Sodium Channels/drug effects
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